A study was done in Canada to see if brain dopamine is a factor in fibromyalgia. Dopamine is one of many neurotransmitters, molecules that transmit messages from your central nervous system. They injected a saline solution deep into the muscle to produce pain in fibromyalgia patients and healthy control subjects who were matched by age and other factors. Then they looked at the brain using positron emission tomography to see if dopamine was being released in response to the pain. The healthy people did release dopamine, but the fibromyalgia patients did not. In healthy people, the amount of dopamine related to the amount of pain, but there was no relationship for the fibromyalgia patients. It must've been a hard study to get people to sign up for, but it does provide evidence that fibromyalgia patients have an abnormal dopamine response to pain. www.fibroinfoservice.com